Pyrodex: I use 20grns (volume) in my .44 Remington s/s Euroarms. Experimented up to 24 grns, however 20grns pretty good.
Trex and beeswax mixture over ball. Tried wads - shop bought and made my own and various fillers, but settled on aforementioned.
Tried various types of caps, but find Remington number 11's the best.

When using Pyrodex get the gun cleaned well as quick as possible. VERY IMPORTANT IT IS MORE CORROSIVE THAN REAL BLACK POWDER. You may be better going down the 777 avenue, its not as corrosive.

I know someone who has a La Page and forgot to clean it after using 777 - left it for a week NO adverse effects whatsoever. 777 more ooomph though, I think 20% more than B/P and Pyrodex.