Another thing that may be worth considering is how will the plastic age harden? As we know plastics can become brittle with age and even if the plastic isn't subjected to impact it may become less able to withstand the sudden pressure fluctuations a transfer port has to bear. One good thing is that there is going to be little if any significant exposure to U.V. in this particular application. Prolonged U.V. exposure is death to a great many plastics!
According to DuPont figures:
http://www.dupont.com/content/dam/du...%20Mod%203.pdf
Delrin will withstand 106 cycles of 31+MPa in flexural endurance tests at 23 deg C, it remains to be seen what sort of endurance it has at elevated temps and due to the low thermal conductivity repeated shots may well significantly raise the temp of the surface in contact with hot transfer gases. Will it melt if you try to shoot repetitive shots as fast as you can? How would it affect the long term life rather than just the immediate life of the port? Many questions that can only be answered by testing in the specific application as there are no tests published by the manufacturer that are remotely similar to the conditions found in a compression chamber/transfer port.