All loads need working up. I would start with an arbitrary 42 ish and either do a ladder test ro work up on .5gr incerments then fine tune. FWIW these figures are arrived at using specific barrels, barrel lengths, bullets etc. A hell of a lot can change when you put a Barnard action, heavy Lilja 3 groove barrel and Plama brass together with RS52 and a 155gn bullet. Mostly over HME if you are shooting FTR People tend to obsess over flat trajectories, whereas given we mostly shoot at known ranges (hunters excluded, I get that) then a best load would either be for accuracy/comfort, or staying supersonic if over 800 yards.