Having only very recently got myself sorted and set up for loading (hornet and 22 250 initially) I have noticed that the 'universal' reloading supplies appear to be a compromise.
Clearly a manufacturer selling ranges of blocks, funnels etc specifically for every single calibre is a bit of a fools errand however I used this as motivation to finally buy a 3d printer.
The net result is I now own a perfect fitting powder funnel for the hornet and will be modifying the pattern I have for this to suit the 250 as well as a lot of other bits and pieces that can be made 'perfect' as I get better at drawing things in cad.
Admittedly this funnel wasn't my design but it was there to use and according to the author is a revision of the 204 ruger specific funnel he made for himself.
https://ibb.co/BBrZ5Jt
I'm pretty damn chuffed with it!
(and the loading blocks and primer flip trays I printed are also spot on!)