Just a knock on from what Tac was just saying..I had a good try with conicals, in my Rem1858, around 30 years ago and no matter what I tried, I couldn't get them to compare with a good round ball for accuracy.

However, I still have a hankering to do some experiments with full wadcutters in a M/L revolver or my LePage - maybe a short stubby solid base W/C.
The wadcutters certainly shot well in my K38 and .32 target pistols.